Background: Health-related quality of life (HRQL) is classically defined as “the functional effects of a disease and of its ensuing therapy on a patient as perceived by the patient himself”. It is crucial to be considered in management of chronic diseases; asthma included. Objectives: Evaluation of the psychosocial profile and caregivers' perception compared to children's perception of HRQL of an Egyptian sample of children with bronchial asthma Methodology: The current case control study comprised 8-12 years old 40 Egyptian children and their caregivers (their mothers); 20 known asthmatics of both sexes as Group I and 20 clinically physically healthy children of comparable age and sex and their caregivers (their mothers) as controls (group II). Full clinical assessment, pulmonary function testing, psychometric evaluation, and assessment of Pediatric Quality of Life using an Arabic validated version of PedsQL™ Inventory both Child Self Report and Parent Proxy Report were carried out for all enrolled children. Results: Total HRQOL score and all its sub-scores (both child and parental reports) were significantly lower in asthmatics compared to controls. HRQOL total score was negatively correlated with anxiety and depression scores and positively correlated with FEV1 and FEF 25%-75%. Moreover, caregivers reported significantly lower scores of the total HRQOL as well as its all assessed sub-scales compared to their asthmatic children self reports. Conclusion: childhood asthma has lead to significant lowering of the total HRQOL and all its sub scales in the studied Egyptian sample of asthmatic children with worse caregivers' perception compared to their asthmatic children's perception.

Author Name: Eman Ahmed Zaky, Malak A Shaheen, Nermine H Amr, Samer Mm El Amp Ndash Said

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Keywords: Health Related Quality of Life (HRQL), Bronchial asthma, Pediatric bronchial asthma, caregivers of asthmatic children.

ISSN: 2249-555X

EISSN: 2249-555X

EOI/DOI: 10.15373/2249555X

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