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Microwave-assisted multicomponent reaction for the synthesis of 2-amino-4H-chromene derivatives using ilmenite (FeTiO3) as a magnetic catalyst under solvent-free conditions

A green and highly efficient method has been developed for the synthesis of 2-amino-4H-chromene derivatives in the presence of FeTiO3 as magnetic catalyst via one-pot three-component condensation reaction of aromatic aldehydes, malononitrile and ?- or ?-naphthol without solvent under microwave irradiation. Mild reaction conditions, short reaction times, simple work-up, use of an economically convenient catalyst, and excellent product yields are the advantageous features of this method. The catalyst can be easily recovered by a simple magnetic separation and can be recycled six times with no significant loss of catalytic activity.



Real Time Impact Factor: Pending

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Keywords: 2-Amino-4H-chromenes; Ilmenite; Three-component reaction; Microwave irradiation

ISSN: 2588-4328

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EOI/DOI: 10.22631/ajgc.2017.93142.1006


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