The combination of isatins, active methylene reagents and 4-phenylurazole/ phthalhydrazide in the presence of ionic liquid ([BMIm]Cl) as a solvent catalyst was found to be a suitable and efficient method for the synthesis of the biologically important spirooxindoles. The features of this procedure were characterized by one-pot procedure, reasonable reaction times, fairly high yields, and simple isolation procedures. The ionic liquid can be easily separated and reused for several times.
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Author Name: Leila Youseftabar-Miri; Hamide Hosseinjani-Pirdehi
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Keywords: Ionic liquid; Multi-Compound Reactions; Spirooxindole; Isatin; Pyrazole
ISSN: 2588-4328
EISSN:
EOI/DOI: 10.22631/ajgc.2017.95721.1017
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