Phosphodiesterase-IV (PDE- IV) inhibitors which are effective anti-inflammatory agents have forced researchers to find new PDE-IV inhibitors with less adverse effects than conventional anti-inflammatory drugs. Some pyridazinone derivatives reduced inflammation by inhibiting PDE-IV enzyme and acted as anti-inflammatory agents. The new pyridazinone derivatives will be more suitable than the currently developed pyridazinone compounds for future studies and could be developed as more safe anti-inflammatory drugs for humans.
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Author Name: Mohammad Asif; . Abida; Md. Tauquir Alam
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Keywords: Phosphodiesterase-4 inhibitor Inflammation Pyridazinone derivatives
ISSN: 2651-4702
EISSN:
EOI/DOI: 10.26655/JMCHEMSCI.2020.2.3
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