The increased use of antibiotics and chemicals with various side effects is now persuading scientists to develop natural substitutes with appropriate effectiveness and protection for humans. V. officinalis rhizomes contain two major constituent groups, including volatile oil sesquiterpens and valpotriates. Valerenic acid can be used to in different disorders such as depression, chronic anxiety, and sleep disorders on the basis of previous stud-ies4. Based on previous literatures, the valerenic acid component had antimicrobial ef-fects on different microorganisms such as Helicobacter pylori, Staphylococcus aureus and Candida albicans and its methanolic extract functions were dose-dependent. Since the antimicrobial activity of V. officinalis in the total extract was correlated with abundant monoterpenoids and sesquiterpenoids, more research on various aspects of pharmaceu-tical effects is suggested.
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Author Name: Zohre Eftekhari
URL: View PDF
Keywords: Valeriana officina-lis, Antibiotic, Anti-microbial
ISSN: 2676-7414
EISSN: 2676-7414
EOI/DOI: 10.29252/pbp.2.1.59
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