An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.
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Author Name: Mitra Saremi
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Keywords: Synthesis, polycarbonyl, efficient
ISSN: 2228-6888
EISSN: 2228-6888
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