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PROTECTIVE EFFECT OF TRIDAX PROCUMBENS L. ON CALCIUM OXALATE UROLITHIASIS AND OXIDATIVE STRESS

In the Indian traditional system of medicine, Tridax procumbens L. is used for treating kidney stone disorders. Ethanolic extract of T. procumbens was evaluated against 0.75% v/v ethylene glycol and 2% w/v ammonium chloride induced calcium oxalate urolithiasis and hyperoxaluria induced oxidative stress in male albino rats. Treatment with the extract was able to reduce caluculogenesis induced urinary excretion and renal deposition of calcium and oxalate and resultant lipid peroxidation, indicating its antiurolithiatic and antioxidant effects. Results of the present study provide evidence for the claimed use of T. procumbens in the treatment of renal stone disease.



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Keywords: T. procumbens, Urolithiasis, Ethylene glycol/Ammonium chloride, Antiurolithiatic and Antioxidant activities

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EISSN: 2231- 0541


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