Aim: To investigate the visual and tomographic changes in patients undergoing pan retinal photocoagulation (PRP) for proliferative diabetic retinopathy (PDR) with or without clinically significant macular edema (CSME).
Methods: This was a prospective, interventional clinical trial including 78 eyes of 78 patients suffering from diabetic retinopathy (DR). All patients were divided into three groups based on the severity of diabetic retinopathy and presence of clinically significant macular edema (CSME). Laser was administered as per the ETDRS standards. Visual acuity (VA), Central macular thickness (CMT), HbA1c and other parameters recorded pre and post laser.
Results: Mean BCVA decreases from 0.24 to 0.33 at one month (p<0.001) and improved to 0.27 (p>0.05) after 4 months in group 1. In group 2 mean BCVA improved from 0.57 to 0.44 at one month (p<0.001) and further improved to 0.39 at four months (p<0.001). In group 3 it deteriorated from 0.63 to 0.67 (p>0.05) but improved to 0.61 at four months (p>0.05). Mean CMT in group one increased from 235? to 277? (p<0.001) but decreased to 253? (p>0.05). From group 2 mean CMT decreased from 379? to 325? at one month (p<0.001) and further decreased to 318? at four months (p<0.001). In group 3 also mean CMT increased from 374 ? to 382? at one month (p>0.05) and then decreased to 373? (p>0.05). Conclusion: Laser photocoagulation still remains the gold standard treatment modality in cases of proliferative diabetic retinopathy (PDR) and in treatment of CSME.
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Author Name: Anukul Dixit, Ishan Yadav, Rajendra P Maurya, M. K. Singh, S. K. Singh.
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Keywords: Pan retinal photocoagulation, proliferative diabetic retinopathy, clinically significant macular edema, Central macular thickness.