The hemostasis of the maternal body differs from the one outside
the pregnancy period. The hemostasis indicators highlight
during pregnancy both the growth in thrombin production
and fibrinolysis. Thrombopenia and the modifications of the
plasmatic factors as well as of the blood flow don’t trigger any
alterations of the hemostasis during pregnancy but point out
the presence of diseases either associated to or induced by
pregnancy. They can also lead to a worsening of these diseases.
It is worth mentioning the presence of the clinical risk factors for
a thrombotic accident (according to Virchow’s classical criteria)
to which the biological factors are added as a consequence
of the acquired or congenital thrombophilia. The thrombotic
syndrome is considered to be the cause of a series of obstetrical
accidents: repeated abortion, premature birth, intrauterine
growth restriction, foetus decease in uterus, preeclampsia, the
HELLP syndrome, DPPNI. The antithrombotic treatment, both
clinically and biologically justified, not only prophylactic but also
curative, can lead to an improvement of the obstetrical results.
Real Time Impact Factor:
Pending
Author Name: Mitran M, Georgescu C, Vladareanu S
URL: View PDF
Keywords: pregnant, coagulation disorders, thrombosis, obstetrical risk, treatment
ISSN: 2457-3566
EISSN: 2457-3566
EOI/DOI:
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