The present investigation was undertaken to evaluate the in-vitro antimicrobial potential of extracts of Adhatoda vasica Nees. leaves against some selected human pathogens causing infections of UT, GIT and skin. N-hexane, methanol and water were used as solvent for the extraction in a successive manner. Agar well diffusion method was employed for evaluation of antimicrobial potentials. The minimum inhibitory (MIC) concentration of the test agents was determined by serial dilution method. The methanolic extract showed maximum antibacterial activity against Streptococcus mitis (19 ± 0.53 mm) and minimum against Micrococci (11 ± 0.41 mm) where as exhibited maximum antifungal activity against C. tropicalis (20 ± 0.68 mm) and minimum against Cryptococcus (15 ± 0.43 mm).
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Author Name: B. Pradhan, D. Bhatt, S.K. Mishra and S. Sahoo
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Keywords: Adhatoda vasica, agar well diffusion method, serial dilution method, MIC
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EISSN: 2394-0859
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