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Diagnostic Accuracy of PCR-Based Detection Tests for Helicobacter Pylori in Otitis Media: A Meta-Analysis

Helicobacter pylori (H. Pylori) infection has serious consequences such as peptic ulcers and gastric cancer [1-3]. Histologic identification remains the gold standard in diagnosing H. pylori infection [4]. The urea breath test, polymerase chain reaction (PCR), and CLO are also the most reliable diagnostic techniques for H. pylori infection [5]. Some researchers reported the association between H. pylori infection and upper respiratory diseases, including chronic rhino sinusitis, chronic otitis media, and chronic otitis media with effusion [6-12], but little is known about the true colonization and the localization of these bacteria in the upper respiratory tract tissue.



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Keywords: Diagnostic accuracy; Meta-analysis; H. Pylori infection; Otitis media with effusion (OME); Polymerase chain reaction (PCR); Histology

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EISSN: 1747-0862.1000062


EOI/DOI: 10.4172/1747-0862.1000062


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